| ADAPTT | Comprehensive ascertainment of bleeding in patients prescribed different combinations of dual antiplatelet therapy (DAPT) and triple therapy (TT, DAPT plus an anticoagulant) after coronary interventions in the UK: a population based cohort study |
| ADEPT | Guided Self-Help for Depression in adults with Autism: A feasibility RCT |
| AIRWAYS-2 | Cluster randomised trial of the clinical and cost effectiveness of the i‐gel supraglottic airway device versus tracheal intubation in the initial airway management of out of hospital cardiac arrest |
| ARCADIA | Association of non-coding RNAs with Coronary Artery Disease and type 2 Diabetes |
| AMIST | A multicentre randomised controlled trial of minimally invasive direct coronary bypass grafting versus percutaneous transluminal coronary angioplasty with stenting for proximal stenosis of the left anterior descending coronary artery |
| BEE | Which is the best type of moisturiser to prescribe for treating the symptoms of childhood eczema – a lotion, cream, gel or ointment? |
| BHACAS 1&2 | Early and midterm outcome after off-pump and on-pump surgery in Beating Heart Against Cardioplegic Arrest Studies (BHACAS 1 and 2): a pooled analysis of two randomised controlled trials |
| BLUEBELLE | A feasibility study of three wound dressing strategies in elective and unplanned surgery |
| CAIRO | Improving Outcomes from Out of Hospital Cardiac Arrest: The Cardiac Arrest Individual Registry and Outcomes (CAIRO) Programme |
| CHICO | Improving the treatment and care of children attending GP practices with coughs and acute respiratory tract infection (RTI) |
| CODEC | Investigation of neural mechanisms of COgnitive DEcline after Cardiac surgery with resting state fMRI: A Pilot study |
| COPTIC | Coagulation and platelet laboratory testing in cardiac surgery |
| COMICS | Conventional versus Minimally Invasive extra-corporeal circulation in patients undergoing Cardiac Surgery: a randomised controlled trial |
| CRISP | Coronary artery grafting in High Risk patients randomised to Off Pump or On Pump Surgery |
| CORTISOL | Ultradian rhythms of cortisol after cardiac surgery |
| CORTISOL 2 | Cortisol profiles in the critically ill after cardiac surgery |
| DECISION | Detection of Coagulopathy in Paediatric Heart Surgery |
| ECHOES | The Effectiveness of Community versus Hospital Eye Service follow-up for patients with neovascular age-related macular degeneration with quiescent disease: a virtual trial |
| ERICCA | Effect of Remote Ischaemic preConditioning on clinical outcomes in patients undergoing Coronary Artery Bypass Graft surgery (ERICCA): A multicentre randomised controlled clinical trial |
| EVALUATE | Evaluation of multi parametric magnetic resonance imaging for characterising lymph node status, peritoneal and liver metastasis in pancreatic cancer |
| EVARREST | A Single‐blinded, Randomized, Controlled, Comparative Phase III Study Evaluating the Safety and Effectiveness of EVARREST™ Fibrin Sealant Patch as an Adjunct to Hemostasis During Cardiovascular Surgery |
| HARVEST | A randomised controlled trial to assess the extent of intimal Hyperplasia and Atherogenesis in bypass Vein grafts following different Surgical preparation Techniques |
| HepCATT | Evaluation of interventions designed to increase diagnosis and treatment of patients with Hepatitis C virus infection in primary care. |
| INFORM | A multi-centered randomised trial to compare 1 stage with 2 stage revision surgery for prosthetic hip joint infection |
| IVAN | A randomised controlled trial of alternative treatments to Inhibit VEGF in Age-related choroidal Neovascularisation (IVAN) |
| IVAN Follow Up | Five year observational follow-up of the IVAN trial cohort: a study of function and morphology |
| INVITE | The effectiveness on post-operative recovery of using ‘off pump’ self-expanding tissue valves (IPVR) versus ‘on pump’ conventional tissue valves (PVR) for pulmonary valve replacement: an early phase randomised controlled trial (RCT) |
| MAGENTA | Testing whether a treatment that we use for CFS/ME called “Graded Exercise Therapy” is effective and value for money. |
| MONARCH | Monitoring for neovascular Age-related macular degeneration (AMD) Reactivation at Home |
| MONITOR | Effectiveness and cost-effectiveness of serum B-type natriuretic peptide (BNP or NT-BNP) testing and monitoring in patients with heart failure (HF) in primary and secondary care |
| NAPSACC | A feasibility cluster randomised controlled trial in child care settings to increase physical activity and healthy eating in 2-4 year olds |
| OXFORD ARTERY | Role of potassium channels in sustaining physiological responses of human resistance arteries |
| OXIC2 | A randomised controlled trial to compare normoxic versus standard cardiopulmonary bypass in cyanotic children undergoing cardiac surgery |
| PASPORT | Patient-specific cerebral oxygenation monitoring as part of an algorithm to reduce transfusion during heart valve surgery: a randomised controlled trial |
| PEACOCK | Hypothalamic-pituitary-adrenal (HPA) axis: function and control mechanisms in children undergoing cardiac surgery |
| PINPOINT | A study of platelet inhibition, using a ‘point of care’ platelet function test, following primary percutaneous coronary intervention for ST elevation myocardial infarction |
| PIPA | Benefit to patients and the NHS of cardiac magnetic resonance imaging (CMR) after Primary percutaneous coronary Intervention (PPCI) Pathway Activation |
| PLAN-A | Exercise intervention in adolescent girls |
| PROMIS | Progenitor cell response after Myocardial Infarction Study |
| PROMPT | Propofol cardioplegia for Myocardial Protection Trial |
| RADAR | Reducing Alzheimer’s Disease through Angiotensin TaRgetting |
| RAFT | Reducing Arthritis Fatigue – clinical Teams using cognitive-behavioural approaches |
| REST | The Runny Ear Study (REST) will focus on children who have middle ear infections with discharge (AOMd) – please note this study is now closed to recruitment |
| ROMIO | The Renoprotective value of Leukodepletion in Heart Valve surgery: an external feasibility randomised controlled trial |
| ROLO | Randomised Oesophagectomy: Minimally Invasive or Open |
| SIPS | Surgical Interventions to treat Severe Pressure Ulcers |
| SKARF | Determination of the SK channel composition contributing to atrial action potential duration and of predictors of response to treatments in patients with or without atrial fibrillation |
| STAR | Support and Treatment After Knee Replacement |
| STET | A randomised controlled trial of median sternotomy vs. anterolateral left thoracotomy on morbidity and healthcare resource use in patients having off-pump coronary artery bypass surgery |
| TARGET | Randomised controlled trial to compare the diagnostic yield of Positron Emission Tomography Computed Tomography (PET-CT) TARGETed pleural biopsy versus CT-guided pleural biopsy in suspected pleural malignancy |
| TEMPLATE | A Randomised Controlled Trial Investigating the Pharmacodynamic Effect of Ticagrelor Monotherapy on Platelet Reactivity in Patients with Coronary Artery Disease: The TEMPLATE Study |
| TEST | TEST (Trial of Eczema allergy Screening Tests) is a feasibility study to help determine if routine allergy tests can help treatment of children with eczema. |
| THERMIC2 | A Randomised Controlled Trial to Compare Normothermic Versus Hypothermic Cardiopulmonary Bypass in Children Undergoing Open Heart Surgery |
| THERMIC3 | Intermittent Antegrade Warm Blood versus Cold Blood Cardioplegia in Children Undergoing Open Heart Surgery: A Prospective, Multicentre, Randomised Controlled Trial |
| Travel to Work | The effectiveness and cost effectiveness of an employer-led intervention to increase walking during the daily commute: Cluster randomised controlled trial. See outputs to this study. |
| TITRE2 | A multi-centre randomised controlled trial of Transfusion Indication Threshold Reduction on transfusion rates, morbidity and healthcare resource use following cardiac surgery |
| TRIUMPH | TReating Urinary symptoms in Men in Primary Healthcare |
| VERDICT | Preoperative Volume Replacement vs. usual care in Diabetic patients having CABG surgery: a randomised controlled trial |
| VICI | Clinical efficacy and mechanistic evaluation of Eplerenone for central serous chorio-retinopathy – the VICI randomised trial |
| VICTORY | Prospective, randomised, controlled investigation comparing the safety and performance of 032-11 surgical haemostat 2g applicator with FLOSEAL hemostatic matrix as an adjunctive haemostat in cardiac surgery and thoracic surgery |
| VIOLET | Video Assisted Thoracoscopic Lobectomy Versus Conventional Open Lobectomy For Lung Cancer, A Multi-Centre Randomised Controlled Trial With An Internal Pilot |
| UNBLOCS | A randomised controlled trial to determine the clinical and cost effectiveness of thulium laser transurethral vaporesection of the prostate (ThuVARP) versus transurethral resection of the prostate (TURP) in the National Health Service (NHS) |
| WISE | A cluster randomised controlled trial evaluating an intervention to improve the mental health support and training available to secondary school teachers |