Our studies

The Bristol Trials Centre is able to support a diverse range of studies across the regulatory framework.

A wide portfolio

Our current portfolio demonstrates diversity in:

  • Setting: Primary, secondary (including emergency settings) and social care (including schools and care homes).
  • Reach: National and international.
  • Population: Adults and vulnerable populations (including people without capacity and children).
  • Trial design: Drug and device studies, RCTs (non CTIMPs) and observational studies.

Therapeutic areas

Our current studies include:

  • cancer
  • general surgery
  • orthopaedic surgery
  • cardiac surgery
  • infection
  • antibiotic use
  • mental health
  • vaccinations
  • renal
  • domestic violence
  • preterm birth
  • dietary advice
  • neuro-development

All studies to date

Studies A-E

ADEPT-2

  • Setting: primary and secondary care
  • Population: adults
  • Reach: UK multi-site
  • Trial design: RCT (non-CTIMP)
  • Therapeutic area: mental health
Status: follow-up

AFRI-c

  • Setting: community, social care
  • Population: adults
  • Reach: UK multi-site
  • Trial design: RCT (non-CTIMP)
  • Therapeutic area: public health and prevention
Status: analysis

ASPECT

  • Setting: secondary care
  • Population: adults
  • Reach: UK multi-site
  • Trial design: CTIMP
  • Therapeutic area: acute respiratory infection
Status: recruiting

ASTUTE

  • Setting: tertiary care
  • Population: adults
  • Reach: UK multi-site
  • Trial design: CTIMP
  • Therapeutic area: ocular inflammation
Status: follow-up

ATHENA

  • Setting: primary care
  • Population: adults
  • Reach: UK multi-site
  • Trial design: CTIMP
  • Therapeutic area: infection
Status: recruiting

CAMELOT

  • Setting: tertiary care
  • Population: adults
  • Reach: UK multi-site
  • Trial design: RCT (non-CTIMP)
  • Therapeutic area: anaethesia, perioperative medicine and pain management
Status: recruiting

CIPHER

  • Setting: secondary care
  • Population: adults
  • Reach: UK multi-site
  • Trial design: observational
  • Therapeutic area: colorectal surgery
Status: analysis

CO2

  • Setting: secondary care
  • Population: adults
  • Reach: UK multi-site
  • Trial design: CTIMP
  • Therapeutic area: surgery
Status: recruiting

CoMiT-ED

  • Setting: secondary care
  • Population: 16 years and over
  • Reach: UK multi-site
  • Trial design: RCT (non-CTIMP)
  • Therapeutic area: emergency medicine
Status: recruiting

CONSEPT

  • Setting: secondary care
  • Population: 16 years and over
  • Reach: UK multi-site
  • Trial design: RCT (non-CTIMP)
  • Therapeutic area: pleural disease
Status: recruiting

CORAL

  • Setting: primary care
  • Population: adults
  • Reach: UK multi-site
  • Trial design: CTIMP
  • Therapeutic area: cardiovascular disease
Status: set-up

CORT-Monitor

  • Setting: secondary care
  • Population: healthy volunteers
  • Reach: UK single-site
  • Trial design: observational
  • Therapeutic area: surgery
Status: recruiting

EPIToPE

  • Setting: secondary care
  • Population: adults
  • Reach: UK single-site
  • Trial design: observational
  • Therapeutic area: all liver conditions
Status: analysis

Studies F-L

H4RT

  • Setting: secondary and tertiary care
  • Population: adults
  • Reach: UK multi-site
  • Trial design: RCT (non-CTIMP)
  • Therapeutic area: renal disorders
Status: follow-up

HIPPY

  • Setting: tertiary care
  • Population: adults
  • Reach: UK multi-site
  • Trial design: RCT (non-CTIMP)
  • Therapeutic area: muskuloskeletal disorders
Status: recruiting

HOME

  • Setting: secondary care
  • Population: adults
  • Reach: UK single-site
  • Trial design: RCT (non-CTIMP)
  • Therapeutic area: cardiothoracic surgery
Status: analysis

IMPPP

  • Setting: primary care
  • Population: adults
  • Reach: UK multi-site
  • Trial design: RCT (non-CTIMP)
  • Therapeutic area: health service research
Status: follow-up

INSPIRE

  • Setting: secondary care
  • Population: adults
  • Reach: UK multi-site
  • Trial design: RCT (non-CTIMP)
  • Therapeutic area: surgery
Status: analysis

INTERACT

  • Setting: primary care
  • Population: adults
  • Reach: UK single-site
  • Trial design: RCT (non-CTIMP)
  • Therapeutic area: mental health
Status: follow-up

IPAP-UTI

  • Setting: primary care
  • Population: adults
  • Reach: UK multi-site
  • Trial design: RCT (non-CTIMP)
  • Therapeutic area: mental health
Status: set-up

IRIS+ Trial

  • Setting: primary care
  • Population: adults
  • Reach: UK multi-site
  • Trial design: RCT (non-CTIMP)
  • Therapeutic area: domestic violence
Status: set-up

Leader-Pad

  • Setting: secondary care
  • Population: adults
  • Reach: UK single-site
  • Trial design: international
  • Therapeutic area: Cardiovascular disease
Status: set-up

LIFT

  • Setting: primary care
  • Population: 16 years and over
  • Reach: UK multi-site
  • Trial design: RCT (non-CTIMP)
  • Therapeutic area: health service research
Status: follow-up

LOLIPOP

  • Setting: secondary care
  • Population: adults
  • Reach: international
  • Trial design: CTIMP
  • Therapeutic area: Anaethesia, perioperative medicine and pain management
Status: recruiting

Studies M-S

MARS2

  • Setting: secondary care
  • Population: adults
  • Reach: UK multi-site
  • Trial design: RCT (non-CTIMP)
  • Therapeutic area: lung cancer
Status: completed

MERIT

  • Setting: primary care
  • Population: 16 years and over
  • Reach: UK single-site
  • Trial design: RCT (non-CTIMP)
  • Therapeutic area: critical care
Status: analysis

NAP SACC UK

  • Setting: nursery schools
  • Population: 2 years and over
  • Reach: UK multi-site
  • Trial design: RCT (non-CTIMP)
  • Therapeutic area: public health and prevention
Status: analysis

PART

  • Setting: secondary care
  • Population: adults
  • Reach: UK multi-site
  • Trial design: RCT (non-CTIMP)
  • Therapeutic area: elective orthopaedic surgery
Status: recruiting

PARTNER

  • Setting: secondary care
  • Population: pregnant people
  • Reach: UK multi-site
  • Trial design: Device
  • Therapeutic area: maternal medicine
Status: set-up

PIONEER

  • CTIMPSetting: secondary care
  • Population: pregnant people
  • Reach: UK multi-site
  • Trial design: Device
  • Therapeutic area: preterm birth
Status: recruiting

Prepare for Kidney Care

  • Setting: secondary and tertiary care
  • Population: adults
  • Reach: UK multi-site
  • Trial design: RCT (non-CTIMP)
  • Therapeutic area: renal disorders
Status: follow-up

PROMPT2

  • Setting: tertiary care
  • Population: adults
  • Reach: UK multi-site
  • Trial design: CTIMP
  • Therapeutic area: cardiac surgery
Status: analysis

RADICAL

  • Setting: secondary care
  • Population: adults
  • Reach: UK multi-site
  • Trial design: RCT (non-CTIMP)
  • Therapeutic area: anaesthesia, perioperative medicine and pain management
Status: recruiting

RAMON

  • Setting: tertiary care
  • Population: adults
  • Reach: UK multi-site
  • Trial design: RCT (non-CTIMP)
  • Therapeutic area: lung cancer
Status: follow-up

RAPID-TEST

  • Setting: primary care
  • Population: 1 year and over
  • Reach: UK multi-site
  • Trial design: RCT (non-CTIMP)
  • Therapeutic area: infection
Status: follow-up

REPROVIDE

  • Setting: community, social care
  • Population: adults
  • Reach: UK single-site
  • Trial design: RCT (non-CTIMP)
  • Therapeutic area: domestic violoence
Status: analysis

ROSE

  • Setting: tertiary care
  • Population: adults
  • Reach: UK multi-site
  • Trial design: RCT (non-CTIMP)
  • Therapeutic area: cancer (upper GI)
Status: set-up

STRATA

  • Setting: primary and secondary care
  • Population: adults
  • Reach: UK multi-site
  • Trial design: CTIMP
  • Therapeutic area: developmental disorders (autism)
Status: follow-up

SUNFLOWER

  • Setting: primary and secondary care
  • Population: adults
  • Reach: UK multi-site
  • Trial design: RCT (non-CTIMP)
  • Therapeutic area: hepato-pancreato-biliary surgery
Status: follow-up

Studies T-Z

TADPOLE

  • Setting: secondary care
  • Population: adults
  • Reach: UK multi-site
  • Trial design: RCT (non-CTIMP)
  • Therapeutic area: breast cancer
Status: set-up

TIGER

  • Setting: primary care
  • Population: children
  • Reach: UK multi-site
  • Trial design: CTIMP
  • Therapeutic area: allergy, infection and immunity
Status: recruiting

ZosterFluCov

  • Setting: secondary care
  • Population: adults
  • Reach: UK multi-site
  • Trial design: CTIMP
  • Therapeutic area: vaccines
Status: recruiting